2-(4-Bromophenyl)-5-phenylthiophene(CAS: 118621-30-0)

2-(4-Bromophenyl)-5-phenylthiophene is a crystalline solid with a molecular weight of approximately 274.06 g/mol. It has low water solubility and moderate solubility in common organic solvents like dichloromethane and chloroform. This compound exhibits reduced reactivity compared to its parent thiophene, showing limited electrophilic substitution reactivity due to its bulky nature.

2-(4-Bromophenyl)-5-phenylthiophene is synthesized via the reaction of 4-bromophenylacetylene with phenyl sulfide under palladium-catalyzed coupling conditions. The synthesis typically involves a cross-coupling reaction with excellent yield and selectivity, making it a suitable method for producing this compound.

2-(4-Bromophenyl)-5-phenylthiophene is utilized in the pharmaceutical industry for its potential as a precursor in drug synthesis. It is also employed in the semiconductor industry for fabricating organic thin-film transistors and photovoltaic devices. Additionally, it has applications in the polymer industry for developing novel materials with specific electronic properties.

When handling 2-(4-Bromophenyl)-5-phenylthiophene, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a well-ventilated area and handled in a fume hood to minimize inhalation exposure. Spills should be cleaned up using appropriate absorbent materials and disposing of the waste according to local regulations. For detailed safety information, refer to the Material Safety Data Sheet (MSDS/SDS).