1-naphthalenediazonium, 2-hydroxy-4-sulfo-, inner salt(CAS: 887-76-3)

1-naphthalenediazonium, 2-hydroxy-4-sulfo-, inner salt has a crystalline form and a molecular weight of approximately 301.11 g/mol. It is mildly soluble in water and has a pKa of 10.1. This inner salt is reactive towards nucleophiles and can undergo diazo displacement reactions. It is typically stored in cool, dark places to prevent photodegradation.

1-naphthalenediazonium, 2-hydroxy-4-sulfo-, inner salt is typically synthesized by diazotization of 1-naphthol and subsequent sulfonation. The diazotization is carried out in an acidic medium using sodium nitrite and sulfuric acid. The sulfonation step is conducted with sulfur trioxide in pyridine. The reaction is monitored by TLC and the product is recrystallized from water to obtain the inner salt.

1-naphthalenediazonium, 2-hydroxy-4-sulfo-, inner salt is used in the pharmaceutical industry for the synthesis of certain drugs and intermediates. It is also utilized in the production of dyes and pigments, as a precursor in organic synthesis, and as a reagent in analytical chemistry for spectroscopic studies and as a sensitizer in photochemistry.

When handling 1-naphthalenediazonium, 2-hydroxy-4-sulfo-, inner salt, use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation of fumes. Store the compound in a cool, dry place away from direct sunlight. In case of a spill, neutralize with an appropriate base and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling instructions.