Compound Q&A

How is 1-naphthalenediazonium, 2-hydroxy-4-sulfo-, inner salt (CAS: 887-76-3) typically synthesized?

Answer

1-naphthalenediazonium, 2-hydroxy-4-sulfo-, inner salt
1-naphthalenediazonium, 2-hydroxy-4-sulfo-, inner salt is typically synthesized by diazotization of 1-naphthol and subsequent sulfonation. The diazotization is carried out in an acidic medium using sodium nitrite and sulfuric acid. The sulfonation step is conducted with sulfur trioxide in pyridine. The reaction is monitored by TLC and the product is recrystallized from water to obtain the inner salt.

About

CAS No 887-76-3
English Name 1-naphthalenediazonium, 2-hydroxy-4-sulfo-, inner salt
Molecular Formula C10H6N2O4S
Molecular Weight 252.25 g/mol
EINECS 212-958-9
SMILES C1=CC=C2C(=C1)C(=CC(=C2[N+]#N)O)S(=O)(=O)[O-]
InChIKey QHIBNGIZPPHJAT-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43

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