[3-(Methoxycarbonyl)phenyl]boronic acid(CAS: 99769-19-4)

The compound [3-(Methoxycarbonyl)phenyl]boronic acid (CAS: 99769-19-4) is a white crystalline solid with a molecular weight of approximately 224.24 g/mol. It has a low solubility in water (2.5 mg/mL) but is more soluble in organic solvents such as acetonitrile and methanol. The compound exhibits good reactivity in various chemical reactions, particularly in Suzuki coupling reactions due to the presence of the boronic acid moiety.

The compound [3-(Methoxycarbonyl)phenyl]boronic acid (CAS: 99769-19-4) can be synthesized via several methods. One common approach involves the reaction of 3-(methoxycarbonyl)phenylboronic acid pinacol ester with methanol in the presence of a base such as sodium hydride. The yield is generally around 70-75%, and the reaction is performed under an inert atmosphere to prevent oxidation.

The compound [3-(Methoxycarbonyl)phenyl]boronic acid (CAS: 99769-19-4) is widely used in the pharmaceutical industry for the synthesis of drug intermediates due to its reactivity in coupling reactions. It is also utilized in the polymer industry for the synthesis of functional polymers and in sensor technology for detecting specific chemical species. Additionally, it plays a role in the semiconductor industry as a precursor in the manufacturing of certain materials.

When handling [3-(Methoxycarbonyl)phenyl]boronic acid (CAS: 99769-19-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a closed container in a cool, dry place away from direct sunlight. In case of a spill, avoid inhaling the dust and handle it with a fume hood. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.