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N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-(tetrahydro-2H-pyran-4-yloxy)-4-quinazolinamine(CAS: 379231-04-6)

N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-(tetrahydro-2H-pyran-4-yloxy)-4-quinazolinamine
CAS Number

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Basic Information

Molecular Formula
C27H32ClN5O5
Molecular Weight
542.04 g/mol

Physical Properties

Boiling Point
671.25°C at 760 mmHg

Chemical Identifiers

SMILES
CN1CCN(CC1)CCOC2=CC3=C(C(=C2)OC4CCOCC4)C(=NC=N3)NC5=C(C=CC6=C5OCO6)Cl
InChIKey
OUKYUETWWIPKQR-UHFFFAOYSA-N

Database References

MDL Number
MFCD09832698

FAQ

This compound is a crystalline solid with a molecular weight of approximately 649.5 g/mol. It has good solubility in organic solvents such as methanol and dimethylformamide. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is also known to be stable under normal laboratory conditions.
The compound is synthesized using a multi-step process involving the coupling of 5-chloro-1,3-benzodioxol-4-amine with a piperazine derivative, followed by the introduction of a tetrahydro-2H-pyran group and a quinazoline ring. Common catalysts include triphenylphosphine and palladium. The final product is typically obtained with high yield and selectivity.
This compound is primarily used in the pharmaceutical industry for developing new drugs due to its chemical structure. It may also find applications in the semiconductor and sensor industries, although its use in these fields is less common and more specialized.
When handling this compound, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be handled carefully, and the material safety data sheet (MSDS) should be consulted for specific spill cleanup procedures. Avoid contact with eyes and skin, and ensure proper disposal of waste products.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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