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Actinomycin D(CAS: 50-76-0)
CAS Number
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Basic Information
Molecular Formula
C62H86N12O16
Molecular Weight
1255.44 g/mol
Physical Properties
Melting Point
251-253?°C
Boiling Point
1386°C at 760 mmHg
Flash Point
792.1°C
Water Solubility
SOLUBLE
Chemical Identifiers
SMILES
CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
InChIKey
RJURFGZVJUQBHK-IIXSONLDSA-N
Database References
MDL Number
MFCD00005033
FAQ
Actinomycin D, CAS 50-76-0, is a cyclic depsipeptide antibiotic with a molecular weight of approximately 925.65 g/mol. It is sparingly soluble in water and ethanol. Actinomycin D exhibits significant reactivity towards nucleic acids, making it a potent antitumor agent. It typically forms a crystalline solid at room temperature.
Actinomycin D (CAS: 50-76-0) is synthesized through semi-synthetic methods, starting from actinorhodin, a natural product from Streptomyces bacteria. The synthesis involves several steps, including acetylation, cyclization, and modification of the molecule's structure to achieve the desired antitumor activity.
Actinomycin D (CAS: 50-76-0) is primarily used in the pharmaceutical industry for its antitumor properties. It is also used in research for its ability to inhibit DNA and RNA synthesis, making it valuable in molecular biology and genetic studies.
When handling Actinomycin D (CAS: 50-76-0), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be handled with caution using appropriate absorbent materials and followed by thorough cleaning and disposal according to safety data sheet (SDS) guidelines.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
Contact Person
Li Manager
caokunli@163.com