(4R)-4-Fluoro-L-proline(CAS: 21156-44-5)

(4R)-4-Fluoro-L-proline is a chiral amino acid derivative with a 4-fluoro substituent at the α-carbon. It is an important intermediate in the synthesis of pharmaceuticals and other biologically active compounds. It has the chemical formula C5H7FO2N and is a white or off-white crystalline powder with a melting point of about 229°C.

(4R)-4-Fluoro-L-proline is primarily used as a building block in the synthesis of pharmaceuticals, particularly those targeting G-protein coupled receptors (GPCRs). It is also utilized in the development of bioactive compounds and as a research tool in drug discovery and molecular biology.

(4R)-4-Fluoro-L-proline is generally considered safe when handled with appropriate precautions. However, it should be used in a well-ventilated area to avoid inhalation of dust and to prevent skin contact. Protective equipment such as gloves and goggles should be worn to ensure safety.

(4R)-4-Fluoro-L-proline should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to minimize exposure to air and moisture. The temperature should be maintained below 25°C to ensure stability and minimize degradation.