Cefazolin Impurity C(CAS: 56842-77-4)

Cefazolin Impurity C is a crystalline compound with a molecular weight of approximately 328.27 g/mol. It has a solubility of about 10 mg/mL in water and is less soluble in organic solvents. Chemically, it is slightly reactive towards bases and oxidizing agents. It is important to handle it under an inert atmosphere to avoid decomposition.

Cefazolin Impurity C is synthesized through a multistep process involving acylation, reduction, and amidation reactions. Commonly, anhydrous conditions and the use of a catalytic amount of a base such as sodium hydroxide are employed. The overall yield is around 75-85%, with high purity achieved through recrystallization and chromatographic methods.

Cefazolin Impurity C is primarily used in the pharmaceutical industry for quality control and impurity profiling of cephalosporin antibiotics. It is also relevant in analytical chemistry for developing standards and reference materials.

When handling Cefazolin Impurity C, use appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store it in a well-ventilated area and avoid inhaling dust or fumes. In case of spill, neutralize with a suitable reagent and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information.