3-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]propanoic acid(CAS: 1260092-44-1)

3-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]propanoic acid is a crystalline solid with a molecular weight of approximately 334.4 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and methanol. Chemically, it is relatively stable but can hydrolyze under acidic conditions. It shows moderate reactivity in esterification and amide formation reactions.

3-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]propanoic acid is synthesized via a multi-step process involving the protection of the amino group, followed by the introduction of the 2-methyl-2-propanol moiety and subsequent acidification. Commonly, this involves the use of protecting groups like tert-butyldimethylsilyl chloride and acid-catalyzed reactions. The overall yield is around 70-80%.

3-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]propanoic acid is primarily used in the pharmaceutical industry for the synthesis of drug intermediates and in research applications. It can also be used in the polymer industry for specific functionalization of polymers and in the semiconductor industry as a component in certain processing solutions.

When handling 3-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]propanoic acid, it is advisable to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. Ensure adequate ventilation by working in a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials and the incident should be reported to the safety officer. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.