16-Methylene-3,20-dioxo-19-norpregn-4-en-17-yl acetate(CAS: 7759-35-5)

16-Methylene-3,20-dioxo-19-norpregn-4-en-17-yl acetate is a crystalline compound with a molecular weight of approximately 364.49 g/mol. It has a low solubility in water but is soluble in organic solvents like acetone and ethanol. The compound is relatively stable under normal conditions but reacts with strong bases to form the corresponding sodium salt.

16-Methylene-3,20-dioxo-19-norpregn-4-en-17-yl acetate is synthesized via a multi-step process involving the synthesis of the 19-norpregn-4-en-17-yl acetate, followed by methylation and subsequent oxidation. Common catalysts include silver oxide and ceric ammonium nitrate, with yields typically ranging from 70-80%.

16-Methylene-3,20-dioxo-19-norpregn-4-en-17-yl acetate finds application in the pharmaceutical industry as an intermediate in steroid synthesis. It is also utilized in the development of certain agricultural chemicals and as a research reagent in organic chemistry.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 16-Methylene-3,20-dioxo-19-norpregn-4-en-17-yl acetate. Work should be conducted in a well-ventilated area or a fume hood. In case of a spill, it should be immediately cleaned up with appropriate chemicals, and the area should be thoroughly washed down with water. Always consult the Safety Data Sheet (SDS) for specific handling instructions.