Ethyl 3-aminoisonicotinate(CAS: 14208-83-4)

Ethyl 3-aminoisonicotinate (CAS: 14208-83-4) is a crystalline compound with a molecular weight of approximately 194.25 g/mol. It is sparingly soluble in water but soluble in organic solvents like ethanol and acetone. The compound is relatively stable but can undergo hydrolysis in the presence of moisture. It may react with bases to form salts.

Ethyl 3-aminoisonicotinate (CAS: 14208-83-4) is synthesized by the amidation of nicotinic acid with ethylamine. Commonly, this reaction is carried out in the presence of a base like sodium hydroxide to enhance the nucleophilicity of ethylamine. The reaction is typically performed in a solvent like ethanol, with good yield and selectivity.

Ethyl 3-aminoisonicotinate (CAS: 14208-83-4) is primarily used in the pharmaceutical industry for the synthesis of certain medications. It is also used in the production of some organic semiconductors and as a precursor in the development of advanced materials for sensors and electronics.

Proper handling of Ethyl 3-aminoisonicotinate (CAS: 14208-83-4) requires the use of appropriate personal protective equipment (PPE), such as gloves and safety goggles. The compound should be stored in a cool, dry place, away from strong acids and bases. In case of a spill, it should be handled with care, using appropriate cleanup procedures as outlined in the Safety Data Sheet (SDS).