Dimethyl 2,6-pyridinedicarboxylate(CAS: 5453-67-8)

Dimethyl 2,6-pyridinedicarboxylate (CAS: 5453-67-8) is a crystalline solid with a molecular weight of approximately 238.19 g/mol. It has a low solubility in water (0.23 g/100 mL at 25°C) but is soluble in organic solvents like ethanol and acetone. Chemically, it is stable under normal conditions but may react with strong bases.

Dimethyl 2,6-pyridinedicarboxylate (CAS: 5453-67-8) is commonly synthesized via the reaction of 2,6-pyridinedicarboxylic acid with dimethylformamide in the presence of a catalyst such as hydrochloric acid. The process yields a product with high selectivity and good yield, typically around 95%.

Dimethyl 2,6-pyridinedicarboxylate (CAS: 5453-67-8) is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for the production of functionalized polymers, and in the sensor industry for the development of chemical sensors due to its reactivity and stability.

When handling Dimethyl 2,6-pyridinedicarboxylate (CAS: 5453-67-8), it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbents, and proper safety data sheets (SDS) should be referenced for detailed handling instructions.