[4-(Bromomethyl)phenyl]methanol(CAS: 71831-21-5)

[4-(Bromomethyl)phenyl]methanol is a clear, colorless liquid with a molecular weight of approximately 215.02 g/mol. It has a slight aromatic odor and is poorly soluble in water but miscible with many organic solvents. This compound is reactive towards nucleophiles and undergoes electrophilic substitution. It crystallizes in the orthorhombic system. Chemical stability is good under normal storage conditions.

[4-(Bromomethyl)phenyl]methanol is synthesized via the bromination of benzaldehyde followed by reduction of the resulting bromomethylbenzyl alcohol. This process involves the use of reagents like N-bromosuccinimide (NBS) and a catalyst such as benzoyl peroxide. The reaction yields a mixture that undergoes purification by recrystallization or distillation.

[4-(Bromomethyl)phenyl]methanol finds applications in the pharmaceutical industry as an intermediate in the synthesis of certain medications, particularly those involving aromatic compounds. It is also utilized in the polymer industry for modifying properties of polymers and in the semiconductor industry for its use in chemical vapor deposition processes.

When handling [4-(Bromomethyl)phenyl]methanol (CAS: 71831-21-5), it is essential to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled using proper absorbent materials and the site should be cleaned with water and detergent. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.