4-Fluoro-3-(1-piperidinylsulfonyl)benzoic acid(CAS: 311785-51-0)

4-Fluoro-3-(1-piperidinylsulfonyl)benzoic acid (CAS: 311785-51-0) is a crystalline solid with a molecular weight of approximately 335.34 g/mol. It has a pKa of about 4.5 and is poorly soluble in water but more soluble in organic solvents like methanol and ethanol. The compound is known for its reactivity, particularly in nucleophilic substitution reactions.

4-Fluoro-3-(1-piperidinylsulfonyl)benzoic acid (CAS: 311785-51-0) is typically synthesized via a multi-step process, starting from benzoic acid and 1-piperidine sulfonyl chloride, with a yield of around 70-80%. The synthesis involves nucleophilic substitution and involves the use of a phase transfer catalyst to enhance the reaction selectivity.

4-Fluoro-3-(1-piperidinylsulfonyl)benzoic acid (CAS: 311785-51-0) is primarily used in the pharmaceutical industry for the development of anti-inflammatory and analgesic drugs. It is also used in the formulation of certain polymers and as a precursor in the production of sensors and semiconductors.

When handling 4-Fluoro-3-(1-piperidinylsulfonyl)benzoic acid (CAS: 311785-51-0), it is essential to wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or under a fume hood to avoid inhalation. In case of a spill, immediately alert the safety officer and follow the emergency procedures outlined in the safety data sheet (SDS).