6-Chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide(CAS: 58-94-6)

The compound, 6-Chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide (CAS: 58-94-6), is a crystalline solid with a molecular weight of approximately 288.65 g/mol. It has limited water solubility, with a solubility of about 0.05 g/L. It is known to be moderately reactive, particularly with reducing agents. The compound is stable under normal storage conditions but should be protected from strong acids and bases.

6-Chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide (CAS: 58-94-6) is typically synthesized via a multi-step process involving the coupling of 4-chlorobenzothiazole with dimethyl sulfoxide nitrosourea. This process often involves the use of sodium hydride as a catalyst. The yield is generally around 70-80%, with selectivity to the desired product being high.

6-Chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide (CAS: 58-94-6) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the production of certain polymers, sensors, and semiconductors due to its chemical reactivity and stability properties.

When handling 6-Chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide (CAS: 58-94-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or fume hood to prevent inhalation. In case of a spill, it should be cleaned up carefully according to safety data sheet (SDS) guidelines, which recommend the use of absorbent materials and disposal in accordance with local regulations.