6-Methyl-1-benzothiophene-2-carboxylic acid(CAS: 1467-86-3)

6-Methyl-1-benzothiophene-2-carboxylic acid (CAS: 1467-86-3) is a solid with a crystalline form. The molecular weight is approximately 210.24 g/mol. It is slightly soluble in water but soluble in common organic solvents like methanol and ethanol. Chemically, it is reactive towards nucleophiles and can undergo esterification and condensation reactions.

6-Methyl-1-benzothiophene-2-carboxylic acid (CAS: 1467-86-3) can be synthesized by the condensation of 6-methyl-1-benzothiophenecarbaldehyde with formic acid under the presence of a suitable catalyst such as p-toluenesulfonic acid. The reaction is typically performed in a solvent like methanol or ethanol to improve solubility and yield. The product can be purified by recrystallization or column chromatography.

6-Methyl-1-benzothiophene-2-carboxylic acid (CAS: 1467-86-3) is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of active pharmaceutical ingredients (APIs). It is also utilized in the polymer industry for the development of functional polymers and in sensors for its unique chemical properties. Additionally, it plays a role in semiconductor applications due to its electronic properties.

When handling 6-Methyl-1-benzothiophene-2-carboxylic acid (CAS: 1467-86-3), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of fumes. In case of a spill, it should be cleaned up immediately with appropriate absorbent materials and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed safety information.