4-(1-Pyrrolidinyl)pyridine(CAS: 2456-81-7)

4-(1-Pyrrolidinyl)pyridine has a crystalline form and a molecular weight of approximately 178.25 g/mol. It is slightly soluble in water but readily soluble in organic solvents like methanol and ethanol. The compound exhibits basic properties and is reactive towards acidic media. It is stable under normal storage conditions but should be protected from moisture and light.

4-(1-Pyrrolidinyl)pyridine is commonly synthesized via the condensation of pyridine with 1-pyrrolidinecarboxylic acid, using an acid catalyst like hydrochloric acid. The reaction is typically carried out in an organic solvent such as ethanol. The yield is around 70-80%, and the product can be isolated by crystallization.

4-(1-Pyrrolidinyl)pyridine is used in the pharmaceutical industry for the preparation of certain drugs. It is also employed in the synthesis of dyes and pigments, and can be found in the production of organic electronic materials such as organic semiconductors. Additionally, it has applications in the development of sensors and as a precursor in polymer synthesis.

When handling 4-(1-Pyrrolidinyl)pyridine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.