Compound Q&A

How is 4-(1-Pyrrolidinyl)pyridine (CAS: 2456-81-7) typically synthesized?

Answer

4-(1-Pyrrolidinyl)pyridine
4-(1-Pyrrolidinyl)pyridine is commonly synthesized via the condensation of pyridine with 1-pyrrolidinecarboxylic acid, using an acid catalyst like hydrochloric acid. The reaction is typically carried out in an organic solvent such as ethanol. The yield is around 70-80%, and the product can be isolated by crystallization.

About

CAS No 2456-81-7
English Name 4-(1-Pyrrolidinyl)pyridine
Molecular Formula C9H12N2
Molecular Weight 148.21 g/mol
SMILES C1CCN(C1)C2=CC=NC=C2
InChIKey RGUKYNXWOWSRET-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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