(E)-2-(2-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS: 1201905-61-4)

(E)-2-(2-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a colorless liquid with a molecular weight of approximately 224.22 g/mol. It has a high boiling point and low solubility in water but is soluble in organic solvents. This compound is highly reactive due to the presence of the vinyl and boron groups. It is often used in organoboron chemistry and catalytic reactions.

(E)-2-(2-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is synthesized through a Wittig olefination reaction, where a ketone undergoes a reaction with ethoxyvinyl trimethyl borate and a strong base like sodium hydride. The reaction is typically carried out in anhydrous organic solvents at low temperatures, yielding a high purity product with good selectivity and yield.

(E)-2-(2-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is widely used in pharmaceuticals for the synthesis of complex molecules and in polymer chemistry for functionalizing polymers. It is also used in semiconductor manufacturing for etching processes and as a precursor in sensor technology.

Handle (E)-2-(2-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in a well-ventilated area or fume hood due to its flammable nature. Wear appropriate personal protective equipment (PPE), including gloves, lab coat, and eye protection. Store in a cool, dry place away from sources of ignition. In case of spill, neutralize with an appropriate chemical and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.