Compound Q&A

How is (E)-2-(2-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1201905-61-4) typically synthesized?

Answer

(E)-2-(2-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
(E)-2-(2-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is synthesized through a Wittig olefination reaction, where a ketone undergoes a reaction with ethoxyvinyl trimethyl borate and a strong base like sodium hydride. The reaction is typically carried out in anhydrous organic solvents at low temperatures, yielding a high purity product with good selectivity and yield.

About

English Name (E)-2-(2-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Molecular Formula C10H19BO3
Molecular Weight 198.07 g/mol
SMILES B1(OC(C(O1)(C)C)(C)C)C=COCC
InChIKey MRAYNLYCQPAZJN-BQYQJAHWSA-N
Last Updated: 2025-10-13 15:08

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