(S)-10-Hydroxycamptothecin(CAS: 19685-09-7)

(S)-10-Hydroxycamptothecin is a naturally occurring alkaloid derived from the plant Camptotheca acuminata. It has the chemical formula C20H22N2O6 and is known for its potent antitumor properties. This compound is a derivative of camptothecin and is used in cancer research and drug development due to its ability to inhibit DNA topoisomerase I, which is crucial for DNA replication and repair.

(S)-10-Hydroxycamptothecin is primarily used in pharmaceutical research as a potential anticancer agent. It is also employed in medicinal chemistry for drug design and development. Additionally, it serves as a valuable compound in biochemical studies related to DNA metabolism and enzymatic inhibition. Its unique structure makes it a key player in the development of topoisomerase I inhibitors.

While (S)-10-Hydroxycamptothecin is used in research and pharmaceutical settings, it requires careful handling due to its potential toxicity. It may cause skin irritation, eye damage, and respiratory issues upon exposure. Safety standards recommend using appropriate protective equipment and following standard laboratory safety protocols. Always consult safety data sheets for detailed information.

(S)-10-Hydroxycamptothecin should be stored in a cool, dry, and dark place, preferably at 2-8°C. It is sensitive to moisture and light, so it should be kept in a tightly sealed container. Storage in a controlled environment helps maintain its chemical stability and potency. Always follow manufacturer guidelines for optimal storage conditions.