6-Bromo-2(1H)-quinazolinone(CAS: 79885-37-3)

6-Bromo-2(1H)-quinazolinone is a crystalline solid with a molecular weight of approximately 220.03 g/mol. It has a high solubility in organic solvents like methanol and ethanol. Chemically, it is moderately reactive, particularly towards nucleophiles and reducing agents. It exhibits excellent stability under normal storage conditions but should be handled with care due to its potential to react with strong bases.

6-Bromo-2(1H)-quinazolinone is typically synthesized through the bromination of 2(1H)-quinazolinone. This process involves the reaction of 2(1H)-quinazolinone with bromine in the presence of a base such as sodium hydroxide. The yield can be improved using appropriate catalysts and optimizing reaction conditions. The reaction is selective and yields a pure product with good efficiency.

6-Bromo-2(1H)-quinazolinone finds applications in various industries, including pharmaceuticals, where it serves as an intermediate for drug synthesis. It is also used in the development of polymer additives, sensors, and semiconductors. Its unique properties make it valuable in materials science for its potential in functional materials and advanced applications.

When handling 6-Bromo-2(1H)-quinazolinone (CAS: 79885-37-3), it is essential to use appropriate personal protective equipment (PPE), such as gloves, safety goggles, and a lab coat. The substance should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be handled in a well-ventilated area with the use of appropriate containment equipment, and spills should be cleaned up immediately following the manufacturer’s safety guidelines and emergency procedures. Always refer to the Safety Data Sheet (SDS) for detailed safety information.