3-Bromo-4-chlorobenzonitrile(CAS: 948549-53-9)

3-Bromo-4-chlorobenzonitrile is a crystalline solid with a molecular weight of approximately 224.02 g/mol. It has a melting point of about 65-66°C and is slightly soluble in water. It reacts with bases, which can lead to the formation of cyanide. The compound is used in various chemical reactions and has moderate reactivity under certain conditions.

3-Bromo-4-chlorobenzonitrile is typically synthesized through the reaction of 4-chlorobenzonitrile with bromine in the presence of a Lewis acid catalyst such as aluminum bromide. This reaction is selective and yields high purity product. Care should be taken to handle the bromine and ensure proper ventilation.

3-Bromo-4-chlorobenzonitrile is used in the pharmaceutical industry for the synthesis of certain intermediates. It also finds applications in the polymer and sensor industries due to its unique chemical properties. Its use in semiconductors is limited but it can be employed in specialized processes.

When handling 3-Bromo-4-chlorobenzonitrile, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated environment or a fume hood. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling instructions.