2-Pyrimidinecarboximidamide Hydrochloride(CAS: 138588-40-6)

2-Pyrimidinecarboximidamide Hydrochloride is a white crystalline solid with a molecular weight of approximately 201.64 g/mol. It has a solubility of about 1.1 g/100 mL in water at 25°C. This compound shows moderate reactivity, particularly with nucleophiles and bases. It is slightly soluble in common organic solvents like ethanol and acetone.

2-Pyrimidinecarboximidamide Hydrochloride is typically synthesized from 2-pyrimidinecarboxamide and hydrochloric acid. The reaction involves the protonation of the amide to form the chloride salt. Commonly, this is done under mild acidic conditions. The yield is around 85-90%, and the reaction is selective and robust.

2-Pyrimidinecarboximidamide Hydrochloride is used in pharmaceuticals for its potential as an antimicrobial agent and in the development of anti-inflammatory drugs. It is also used in the synthesis of polymers and as a reagent in organic chemistry research. Additionally, it has applications in the production of sensors and semiconductors.

When handling 2-Pyrimidinecarboximidamide Hydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight. Spills should be handled using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.