4-Hydroxy-3-quinolinecarboxylic acid(CAS: 13721-01-2)

4-Hydroxy-3-quinolinecarboxylic acid (CAS: 13721-01-2) is a crystalline solid with a molecular weight of approximately 181.16 g/mol. It is poorly soluble in water but soluble in many organic solvents. The compound is highly reactive and forms complexes with various metal ions. It is known for its acid functionality and can undergo various chemical reactions such as esterification and condensation.

4-Hydroxy-3-quinolinecarboxylic acid (CAS: 13721-01-2) is typically synthesized through the reaction of 3-quinolinecarboxaldehyde with hydroxylamine hydrochloride followed by acidification. The synthesis involves the condensation of the aldehyde with the amine, which then undergoes acid hydrolysis to yield the final carboxylic acid product. The yield from this reaction is typically around 70-80%, with high selectivity towards the desired product.

4-Hydroxy-3-quinolinecarboxylic acid (CAS: 13721-01-2) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those that require acid functionalities. It is also used in the polymer industry for the preparation of functionalized polymers and in the production of sensors and semiconductors due to its unique chemical properties.

Proper handling of 4-Hydroxy-3-quinolinecarboxylic acid (CAS: 13721-01-2) requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or within a fume hood due to its potential for releasing toxic vapors. In case of a spill, the area should be immediately flushed with water and the affected area cleaned properly. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.