5-methyl-2-phenylpyridine(CAS: 27012-22-2)

5-Methyl-2-phenylpyridine (CAS: 27012-22-2) is a solid with a crystalline form. Its molecular weight is approximately 175.23 g/mol. It is slightly soluble in water but soluble in common organic solvents such as ethanol and acetone. This compound exhibits moderate reactivity, particularly in nucleophilic substitution reactions. It is stable under normal conditions but should be handled with care to prevent degradation.

5-Methyl-2-phenylpyridine (CAS: 27012-22-2) is commonly synthesized via a Friedel-Crafts acylation of 2-phenylpyridine with methanol. The reaction is conducted in the presence of a Lewis acid catalyst like aluminum chloride. High selectivity and yield are achieved under these conditions, making this a widely used method in organic synthesis.

5-Methyl-2-phenylpyridine (CAS: 27012-22-2) is used in various industries. It is a key intermediate in pharmaceuticals, where it is used in the synthesis of certain drugs. It also finds applications in the development of sensors and semiconductors due to its unique electronic properties. Additionally, it is utilized in the production of certain polymers where its stability and reactivity are advantageous.

When handling 5-methyl-2-phenylpyridine (CAS: 27012-22-2), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, follow the safety data sheet (SDS) guidelines for cleanup. Dispose of any waste material according to local regulations to ensure environmental safety.