2-Chloro-4-nitropyridine(CAS: 23056-36-2)

CAS Number
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Basic Information
Molecular Formula
C5H3ClN2O2
Molecular Weight
158.54 g/mol
Physical State
Pale-yellow to Yellow-brown Solid
Physical Properties
Melting Point
52.0 to 56.0 deg-C
Boiling Point
258.4℃ at 760 mmHg
Flash Point
223 ºF
Chemical Identifiers
SMILES
C1=CN=C(C=C1[N+](=O)[O-])Cl
InChIKey
LIEPVGBDUYKPLC-UHFFFAOYSA-N
Database References
MDL Number
MFCD00661454
Beilstein Registry Number
120418
FAQ
2-Chloro-4-nitropyridine is a crystalline solid with a molecular weight of 171.56 g/mol. It has a melting point of 150-152°C and is slightly soluble in water. This compound is moderately reactive, especially with reducing agents. It is an important intermediate in organic synthesis and exhibits good solubility in organic solvents like ethanol, acetone, and dichloromethane.
2-Chloro-4-nitropyridine is typically synthesized via the nitration of 2-chloropyridine. The nitration reaction is performed in the presence of a strong acid like sulfuric acid, and the reaction is carried out at an elevated temperature. This method yields a product with high selectivity and good yield, making it a common industrial process for producing this compound.
2-Chloro-4-nitropyridine is used in various industries, including pharmaceuticals, where it serves as an intermediate for the synthesis of certain drugs. It is also utilized in the synthesis of organic semiconductors and in the production of dyes. Additionally, this compound finds applications in the development of sensors and as a reagent in polymer chemistry.
When handling 2-Chloro-4-nitropyridine, it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be stored in a cool, dry place, away from heat and sources of ignition. In the event of a spill, it is recommended to use appropriate absorbents and dispose of the material according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for specific handling and disposal instructions.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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