8-Amino-2-(1H-tetrazol-5-yl)-4H-chromen-4-one(CAS: 110683-22-2)

8-Amino-2-(1H-tetrazol-5-yl)-4H-chromen-4-one is a crystalline compound with a molecular weight of approximately 297.2 g/mol. It has a solubility in water of about 3 mg/mL at 25°C. This compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions and redox reactions. It is stable under normal laboratory conditions but should be stored in a cool, dry place away from direct sunlight.

8-Amino-2-(1H-tetrazol-5-yl)-4H-chromen-4-one can be synthesized using a multi-step procedure involving the condensation of a chromenone derivative with 5-aminotetrazole. The reaction is typically carried out in an aprotic solvent like DMF, with a coupling agent such as EDC. The yield and selectivity of the reaction can be optimized by adjusting the reaction conditions and using appropriate catalysts.

8-Amino-2-(1H-tetrazol-5-yl)-4H-chromen-4-one finds applications in various industries, including pharmaceuticals, as a precursor for drug development, and in sensors for its unique photochemical properties. It is also used in the synthesis of semiconductors due to its electronic properties. Additionally, it plays a role in the development of novel materials for polymer applications.

When handling 8-Amino-2-(1H-tetrazol-5-yl)-4H-chromen-4-one, proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. The compound should be stored in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and the area should be flushed with water. It is important to refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.