Edoxaban Impurity 67(CAS: 143150-92-9)

Edoxaban Impurity 67 (CAS: 143150-92-9) is a crystalline solid with a molecular weight of approximately 522.5 g/mol. It has a low solubility in water but is more soluble in organic solvents like dimethyl sulfoxide (DMSO). Chemically, it is less reactive than the parent compound, edoxaban, making it suitable for specific pharmaceutical applications. Its specific gravity is around 1.3 g/cm³ and boiling point is above 300°C, indicating it is not volatile under typical laboratory conditions.

Edoxaban Impurity 67 (CAS: 143150-92-9) is synthesized through a series of chemical reactions involving the parent compound, edoxaban. The process typically includes steps such as hydrolysis and cyclization, using appropriate catalysts to enhance selectivity and yield. The reaction conditions are carefully controlled to minimize the formation of other impurities, ensuring the purity of the end product.

Edoxaban Impurity 67 (CAS: 143150-92-9) is primarily used in the pharmaceutical industry, specifically in the development and production of edoxaban, an anticoagulant medication. Although it is an impurity, its presence can provide insights into the quality and purity of the final drug product. It may also find applications in research and development for similar anticoagulant therapies.

When handling Edoxaban Impurity 67 (CAS: 143150-92-9), it is important to use proper personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials, and contaminated materials should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.