Tozasertib(CAS: 639089-54-6)

Tozasertib, with CAS number 639089-54-6, is a crystalline compound with a molecular weight of approximately 428.45 g/mol. It has a melting point of 150-155°C and is slightly soluble in water. It is reactive towards basic conditions and shows moderate solubility in common organic solvents like DMSO and methanol. Safe handling in a fume hood is recommended to avoid inhalation and skin contact.

Tozasertib is synthesized through a multi-step process involving protection, functionalization, and deprotection steps. Commonly, the synthesis involves the use of protected amino acids and their derivatives. The reaction conditions include the use of Lewis acids as catalysts to ensure high yield and selectivity. The overall process yields approximately 70-80% of the final product, with purification achieved through column chromatography and recrystallization.

Tozasertib, with CAS number 639089-54-6, is primarily used in the pharmaceutical industry for its potential as a cancer therapeutic. It is also explored in the field of biotechnology for its role in modulating cellular signaling pathways. Additionally, it has applications in the development of diagnostic tools and may be used in the polymer industry for its unique chemical properties.

When handling Tozasertib (CAS: 639089-54-6), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.