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[4-(Trifluoromethyl)phenyl]boronic acid(CAS: 128796-39-4)

[4-(Trifluoromethyl)phenyl]boronic acid
CAS Number

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Basic Information

Molecular Formula
C7H6BF3O2
Molecular Weight
189.93 g/mol

Physical Properties

Melting Point
245-250 °C (lit.)
Flash Point
110.2℃
Water Solubility
Soluble in DMSO, not in water

Chemical Identifiers

SMILES
B(C1=CC=C(C=C1)C(F)(F)F)(O)O
InChIKey
ALMFIOZYDASRRC-UHFFFAOYSA-N

Database References

MDL Number
MFCD00151855
Beilstein Registry Number
3544189

FAQ

[4-(Trifluoromethyl)phenyl]boronic acid (CAS: 128796-39-4) is a boronic acid derivative with the chemical formula C8H8BF3O2. It features a phenyl ring substituted with a trifluoromethyl group at the 4-position, making it highly hydrophobic and reactive in organic synthesis. This compound is commonly used as an intermediate in the development of pharmaceuticals and materials science applications due to its functional group versatility.
[4-(Trifluoromethyl)phenyl]boronic acid (CAS: 128796-39-4) is primarily utilized in pharmaceutical research for synthesizing drugs targeting metabolic disorders and cancer. It also finds applications in agrochemicals, polymer science, and as a coupling agent in Suzuki reactions. Its trifluoromethyl group enhances stability and bioavailability in medicinal compounds.
[4-(Trifluoromethyl)phenyl]boronic acid (CAS: 128796-39-4) is generally considered low toxicity but requires careful handling. It should be used in well-ventilated areas with protective gloves and goggles. While not classified as hazardous under standard safety guidelines, prolonged exposure may cause irritation, so adherence to OSHA and EPA protocols is recommended for safe manipulation.
[4-(Trifluoromethyl)phenyl]boronic acid (CAS: 128796-39-4) should be stored in a cool, dry place (2-8°C) in a sealed container to prevent moisture absorption. Protection from light is essential to maintain stability. Avoid exposure to air and incompatible materials, and ensure storage in a fire-resistant cabinet for safety compliance.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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