Butylboronic acid(CAS: 4426-47-5)

Butylboronic acid is a colorless solid with a molecular weight of approximately 150.2 g/mol. It has a melting point of 48-50°C and is poorly soluble in water but freely soluble in organic solvents like ethanol and acetone. Chemically, it is a weak acid and can participate in various reactions such as esterification and condensation reactions.

Butylboronic acid is typically synthesized by the Grignard reaction of butyl magnesium bromide with boron tribromide. The reaction is carried out in an inert solvent like THF at low temperature. This method provides a high yield and good selectivity for the boronic acid product.

Butylboronic acid is used in various industries, particularly in pharmaceuticals for the synthesis of biologically active compounds, in polymers for the modification of polymer properties, in sensors for detecting specific chemical species, and in the semiconductor industry for the production of high-purity materials.

Butylboronic acid should be handled with care. It is recommended to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of a spill, it should be cleaned up immediately using the appropriate methods and materials. For detailed safety information, refer to the safety data sheet (SDS) for Butylboronic acid (CAS: 4426-47-5).