Ethyl 2-pyridinecarboxylate(CAS: 2524-52-9)

Ethyl 2-pyridinecarboxylate (CAS: 2524-52-9) is a crystalline compound with a molecular weight of approximately 145.17 g/mol. It has a solubility of 0.37 g/100 mL in water. It is moderately reactive, particularly in acidic conditions. This compound is often used in organic synthesis and has low volatility and a boiling point around 190°C.

Ethyl 2-pyridinecarboxylate (CAS: 2524-52-9) can be synthesized via the acylation of 2-pyridinecarboxylic acid with ethyl chloroformate. The reaction is typically catalyzed by a base like triethylamine, with a yield of approximately 75-80%. This method ensures high selectivity and can be performed under mild conditions.

Ethyl 2-pyridinecarboxylate (CAS: 2524-52-9) is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various medications and also finds applications in the production of polymers and organic solvents.

When handling Ethyl 2-pyridinecarboxylate (CAS: 2524-52-9), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area and handled under a fume hood. In case of spillage, immediate cleanup should be performed using absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed safety information.