Kanamycin Sulfate(CAS: 133-92-6)

Kanamycin Sulfate is a white to off-white crystalline powder with a molecular weight of approximately 1129.52. It is sparingly soluble in water and has limited solubility in ethanol. Chemically, it is highly reactive with bases and can undergo hydrolysis. It is often used in pharmaceutical applications due to its antibacterial properties.

Kanamycin Sulfate is synthesized by a fermentation process followed by chemical modification. The fermentation involves the growth of Streptomyces kanamyceticus, which produces the primary kanamycin compound. This is then converted to kanamycin sulfate through a sulfate esterification process. The synthesis typically requires careful control of pH and temperature to achieve high yield and selectivity.

Kanamycin Sulfate is primarily used in the pharmaceutical industry for its antibiotic properties. It is also used in agriculture as a fungicide. Additionally, it has applications in research and development for its biological and chemical properties.

When handling Kanamycin Sulfate, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up carefully with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.