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4-(Benzyloxy)benzaldehyde(CAS: 4397-53-9)

4-(Benzyloxy)benzaldehyde
CAS Number

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Basic Information

Molecular Formula
C14H12O2
Molecular Weight
212.25 g/mol

Physical Properties

Melting Point
71-74 °C (lit.)
Boiling Point
219°C/13mmHg(lit.)
Flash Point
197-199℃/20mm

Chemical Identifiers

SMILES
C1=CC=C(C=C1)COC2=CC=C(C=C2)C=O
InChIKey
ZVTWZSXLLMNMQC-UHFFFAOYSA-N

Database References

MDL Number
MFCD00003387
Beilstein Registry Number
1242385

FAQ

4-(Benzyloxy)benzaldehyde (CAS: 4397-53-9) is a white solid with a molecular weight of 228.23 g/mol. It has a highly polar nature and is sparingly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive, especially towards nucleophilic substitution reactions. It is often used as a substrate in organic synthesis due to its reactivity and stability.
4-(Benzyloxy)benzaldehyde (CAS: 4397-53-9) is typically synthesized by reacting benzoic acid with benzyl alcohol in the presence of a Lewis acid catalyst like aluminum chloride. The reaction selectively forms the benzyl ether linkage, yielding a yield of up to 90%. The process involves careful temperature control and the use of a fume hood for safety.
4-(Benzyloxy)benzaldehyde (CAS: 4397-53-9) is primarily used in the pharmaceutical industry for the synthesis of various drugs, as well as in the polymer industry for the production of functional polymers with improved properties. It also finds applications in sensors and semiconductors due to its unique chemical functionalities.
When handling 4-(Benzyloxy)benzaldehyde (CAS: 4397-53-9), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be immediately contained and cleaned up using appropriate techniques. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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