2-Methyl-2-propanyl tetrahydro-1(2H)-pyrimidinecarboxylate(CAS: 867065-85-8)

2-Methyl-2-propanyl tetrahydro-1(2H)-pyrimidinecarboxylate (CAS: 867065-85-8) is a white crystalline solid. Its molecular weight is approximately 226.31 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. This compound is reactive, particularly towards nucleophiles, and is used in various chemical reactions. It has a pKa of approximately 4.8.

2-Methyl-2-proanyl tetrahydro-1(2H)-pyrimidinecarboxylate (CAS: 867065-85-8) is typically synthesized via a multistep process involving the condensation of 2-methyl-2-propanol with 1,4-pyrimidine-2,5-dione. The reaction is catalyzed by a strong base like sodium hydride, and the yield is around 70-80%. The reaction is highly selective, and the product is isolated by filtration and recrystallization.

2-Methyl-2-proanyl tetrahydro-1(2H)-pyrimidinecarboxylate (CAS: 867065-85-8) is primarily used in the pharmaceutical industry for the synthesis of drugs, particularly those targeting nucleic acid metabolism. It also finds applications in the polymer industry as a monomer for the development of new materials with specific properties. Additionally, it is used in the chemical sensor industry due to its reactivity.

When handling 2-Methyl-2-proanyl tetrahydro-1(2H)-pyrimidinecarboxylate (CAS: 867065-85-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handle in a well-ventilated area or under a fume hood due to its reactivity. Spills should be immediately cleaned up, and the material should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.