2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 5-oxo-, 1,1-dimethylethyl ester, (1R,4R)-(CAS: 1400808-00-5)

(1R,4R)-2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 5-oxo-, 1,1-dimethylethyl ester is a white crystalline solid with a molecular weight of approximately 258.34 g/mol. It has limited water solubility but good solubility in organic solvents such as dichloromethane and ethanol. Chemically, it shows reactivity typical of carboxylic acid esters, including esterification and hydrolysis reactions.

(1R,4R)-2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 5-oxo-, 1,1-dimethylethyl ester can be synthesized via a multistep process involving the formation of the azabicyclic ring, followed by functionalization with a carboxylic group, and esterification with 1,1-dimethylethyl alcohol. The synthesis typically involves the use of reagents such as phthalimide and sodium hydride, and is performed under mild to moderate conditions.

(1R,4R)-2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 5-oxo-, 1,1-dimethylethyl ester is primarily used in the pharmaceutical industry for the synthesis of complex molecules. It also finds applications in the polymer and chemical sensor industries for the development of new materials and sensors.

Handling (1R,4R)-2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 5-oxo-, 1,1-dimethylethyl ester requires caution. Always wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat. Work in a fume hood to avoid inhalation. In case of spill, neutralize with an appropriate absorbent and dispose of the material according to local regulations. Refer to the safety data sheet (SDS) for detailed handling and disposal instructions.