Methyl 4-bromoisoquinoline-1-carboxylate(CAS: 1512077-05-2)

Methyl 4-bromoisoquinoline-1-carboxylate (CAS: 1512077-05-2) is a crystalline compound with a molecular weight of approximately 289.05 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and acetonitrile. The compound is moderately reactive, particularly towards nucleophiles. It is stable under normal storage conditions but should be handled with care due to its bromine content.

Methyl 4-bromoisoquinoline-1-carboxylate (CAS: 1512077-05-2) is typically synthesized through a bromination reaction of 4-aminomethylisoquinoline-1-carboxylic acid. The process involves treating the amine with N-bromosuccinimide (NBS) in the presence of a suitable catalyst under appropriate conditions. The yield can be improved by optimizing the reaction parameters, such as temperature and solvent choice.

Methyl 4-bromoisoquinoline-1-carboxylate (CAS: 1512077-05-2) is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the semiconductor industry for the production of specific organic compounds used in electronic applications and as a precursor in the manufacturing of polymers with unique properties.

When handling Methyl 4-bromoisoquinoline-1-carboxylate (CAS: 1512077-05-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. Fume hoods should be used during handling to minimize exposure to bromine fumes. In case of a spill, neutralize the spill with an appropriate neutralizing agent and dispose of it according to local regulations. Refer to the SDS for detailed safety information.