2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline(CAS: 850567-56-5)

2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 850567-56-5) is a crystalline solid with a molecular weight of approximately 376.21 g/mol. It has a low solubility in water but is more soluble in organic solvents like THF and DMSO. The compound is known for its reactivity in boron-mediated reactions and displays good stability under normal storage conditions.

2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is typically synthesized using a boronate esterification process, involving the reaction of 2-chloroaniline with 1,3,2-dioxaborolane in the presence of a base such as sodium bicarbonate. The reaction is performed under mild conditions to achieve high selectivity and yield.

2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 850567-56-5) is used in the pharmaceutical industry for the synthesis of complex organic molecules, in polymer production for the development of new materials, and in sensor technology for specific chemical detection applications.

When handling 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 850567-56-5), wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Ensure the reaction is carried out in a fume hood. Dispose of any waste according to local regulations and consult the Safety Data Sheet (SDS) for detailed guidelines on handling and disposal.