Compound Q&A
How is 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 850567-56-5) typically synthesized?
Answer
2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is typically synthesized using a boronate esterification process, involving the reaction of 2-chloroaniline with 1,3,2-dioxaborolane in the presence of a base such as sodium bicarbonate. The reaction is performed under mild conditions to achieve high selectivity and yield.
About
CAS No
850567-56-5
English Name
2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
Molecular Formula
C12H17BClNO2
Molecular Weight
253.54 g/mol
SMILES
CC1(C)OB(OC1(C)C)c2ccc(Cl)c(N)c2
InChIKey
KHGJUVPQSMKNFA-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
