5-Bromo-2-pyrazol-1-yl-pyrimidine(CAS: 883230-94-2)

5-Bromo-2-pyrazol-1-yl-pyrimidine is a crystalline compound with a molecular weight of approximately 239.04 g/mol. It has a low solubility in water but is soluble in common organic solvents like DMF, DMSO, and DCM. This compound is relatively stable under normal conditions but can react with strong bases or oxidizing agents. It is commonly used as a precursor in organic synthesis and pharmaceutical applications.

5-Bromo-2-pyrazol-1-yl-pyrimidine is typically synthesized through a multistep reaction starting from 2-pyrazol-1-yl-pyrimidine. The bromination step is usually carried out using N-bromosuccinimide (NBS) in an appropriate solvent. The synthesis also involves the use of a catalyst and involves careful control of reaction conditions to achieve high selectivity and yield.

5-Bromo-2-pyrazol-1-yl-pyrimidine is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drug molecules. It is also utilized in the polymer industry for the development of new materials and in the electronics sector for the production of semiconductors and sensors.

When handling 5-Bromo-2-pyrazol-1-yl-pyrimidine, ensure the use of personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work in a well-ventilated area or a fume hood to prevent inhalation of fumes. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be properly decontaminated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.