L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide(CAS: 87616-84-0)

L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide is a complex peptide with a significant molecular weight of approximately 1340.72 Da. It has a crystalline form and is poorly soluble in water, with solubility dependent on pH. The compound is highly reactive, particularly towards nucleophiles and bases, making it useful in various biochemical and pharmaceutical applications.

L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide is typically synthesized via solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The process involves sequential coupling of protected amino acids, followed by deprotection steps. High yield and selectivity are achieved using appropriate protecting groups and careful control of reaction conditions.

L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide is utilized in the pharmaceutical industry for drug development, particularly in the design of biomolecules and peptides. It is also of interest in the field of materials science, with applications in the synthesis of advanced polymers and sensors, though its direct use in semiconductors is less common.

Handling L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide requires the use of personal protective equipment (PPE), including gloves and safety goggles. It should be stored in a cool, dry place away from direct sunlight and moisture. Spills should be cleaned up with appropriate absorbents, and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.