Compound Q&A

How is L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide (CAS: 87616-84-0) typically synthesized?

Answer

L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide
L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide is typically synthesized via solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The process involves sequential coupling of protected amino acids, followed by deprotection steps. High yield and selectivity are achieved using appropriate protecting groups and careful control of reaction conditions.

About

CAS No 87616-84-0
English Name L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide
Molecular Formula C46H56N12O6
Molecular Weight 873.03 g/mol
SMILES C[C@@H](C(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@@H](Cc4c[nH]c5c4cccc5)NC(=O)[C@H](Cc6c[nH]cn6)N
InChIKey WZHKXNSOCOQYQX-FUAFALNISA-N
Last Updated: 2025-09-08 00:42

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