Ethyl 2-chloro-3-cyano-6-methyl-5-nitroisonicotinate(CAS: 72701-63-4)

CAS Number
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Basic Information
Molecular Formula
C10H8ClN3O4
Molecular Weight
269.64 g/mol
Physical Properties
Melting Point
55℃
Boiling Point
416.4°C at 760 mmHg
Density
1.46
Flash Point
205.6°C
Chemical Identifiers
SMILES
CCOC(=O)C1=C(C(=NC(=C1[N+](=O)[O-])C)Cl)C#N
InChIKey
SEHVSYSJEKTOTF-UHFFFAOYSA-N
Database References
MDL Number
MFCD00052634
FAQ
Ethyl 2-chloro-3-cyano-6-methyl-5-nitroisonicotinate (CAS: 72701-63-4) is a crystalline compound with a molecular weight of approximately 284.69 g/mol. It has a high solubility in organic solvents such as acetone and ethanol. The compound is relatively stable but can react with strong bases and acids. It has a melting point around 130°C and a boiling point around 260°C under reduced pressure.
How is Ethyl 2-chloro-3-cyano-6-methyl-5-nitroisonicotinate (CAS: 72701-63-4) typically synthesized?
Ethyl 2-chloro-3-cyano-6-methyl-5-nitroisonicotinate (CAS: 72701-63-4) is typically synthesized via a multi-step process involving acylation, nitration, and chlorination reactions. These reactions are usually conducted under mild conditions and catalyzed by appropriate reagents to ensure high selectivity and yield.
Ethyl 2-chloro-3-cyano-6-methyl-5-nitroisonicotinate (CAS: 72701-63-4) is primarily used in the pharmaceutical industry for the synthesis of intermediates and raw materials. It is also used in some specialized applications in the polymer and sensor industries due to its unique chemical properties.
When handling Ethyl 2-chloro-3-cyano-6-methyl-5-nitroisonicotinate (CAS: 72701-63-4), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. This compound should be handled in a well-ventilated area or within a fume hood to avoid inhalation of potential fumes. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly washed down. Safety data sheets (SDS) should always be consulted for detailed safety information.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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