4-(6-Methyl-1,3-benzothiazol-2-yl)aniline(CAS: 92-36-4)

4-(6-Methyl-1,3-benzothiazol-2-yl)aniline (CAS: 92-36-4) is a crystalline solid with a molecular weight of approximately 241.22 g/mol. It is slightly soluble in water but has good solubility in organic solvents like ethanol and acetone. The compound exhibits good stability under normal conditions but is reactive towards strong oxidizing agents. It is used in various applications due to its unique chemical properties.

4-(6-Methyl-1,3-benzothiazol-2-yl)aniline (CAS: 92-36-4) is synthesized through a multi-step process involving the coupling of 2-methylbenzothiazole with aniline under basic conditions. The synthesis typically requires the use of sodium hydride as a catalyst, with high selectivity and a yield of around 85%. The reaction is carried out in an inert atmosphere to prevent side reactions.

4-(6-Methyl-1,3-benzothiazol-2-yl)aniline (CAS: 92-36-4) is commonly used in the pharmaceutical industry for the synthesis of certain drugs, particularly those targeting immune modulation and inflammation. It is also used in the sensor industry for developing gas sensors and in polymer applications for enhancing certain mechanical properties. Additionally, it has applications in the semiconductor industry for its role in surface modification and passivation.

When handling 4-(6-Methyl-1,3-benzothiazol-2-yl)aniline (CAS: 92-36-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be stored in a cool, dry place away from heat sources and oxidizing agents. In case of a spill, it should be handled using appropriate containment measures, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.