3-Fluoro-4-nitrobenzoic acid(CAS: 403-21-4)

3-Fluoro-4-nitrobenzoic acid is a white crystalline solid with a molecular weight of 219.06 g/mol. It has a melting point of 225-227°C and is only slightly soluble in water. This compound is reactive towards bases and can undergo esterification and nitration reactions. It is commonly used in organic synthesis as a functional group derivative.

3-Fluoro-4-nitrobenzoic acid can be synthesized by nitration of 3-fluorobenzoic acid followed by esterification. Commonly, 3-fluorobenzoic acid is mixed with nitric acid and sulfuric acid in an appropriate solvent for the nitration process. The product is then converted to the acid form by hydrolysis. This compound can also be prepared via other routes involving aromatic substitution reactions.

3-Fluoro-4-nitrobenzoic acid (CAS: 403-21-4) is used in various industries including pharmaceuticals, where it serves as a precursor for drug synthesis; in the production of dyes and pigments; in the development of sensors and detectors; and in the synthesis of materials for electronic and photonic applications.

When handling 3-Fluoro-4-nitrobenzoic acid, proper personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. It should be stored in a cool, dry place away from direct sunlight and incompatible materials. Spills should be handled with appropriate absorbent material and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.