Methyl 6-oxo-1,6-dihydropyridazine-4-carboxylate(CAS: 89640-81-3)

Methyl 6-oxo-1,6-dihydropyridazine-4-carboxylate (CAS: 89640-81-3) is a white crystalline solid with a molecular weight of approximately 246.23 g/mol. It has a slight solubility in water and is highly soluble in organic solvents. This compound is known for its stability and reactivity in organic synthesis, particularly in reactions involving esterification and ester hydrolysis.

Methyl 6-oxo-1,6-dihydropyridazine-4-carboxylate (CAS: 89640-81-3) can be synthesized via the condensation of methyl acetoacetate with 4-nitropyridazine, followed by reduction and hydrolysis to remove the nitro group. Typical catalysts include palladium on carbon and sodium hydroxide, with high yields and good selectivity reported in literature.

Methyl 6-oxo-1,6-dihydropyridazine-4-carboxylate (CAS: 89640-81-3) is primarily used in the pharmaceutical industry for the synthesis of various drug intermediates. It also finds applications in the polymer industry for the development of new materials with improved mechanical properties, and in the sensor and semiconductor industries for the fabrication of sensitive and efficient devices.

When handling Methyl 6-oxo-1,6-dihydropyridazine-4-carboxylate (CAS: 89640-81-3), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up carefully using absorbent materials, and proper disposal methods should be followed. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal guidelines.