3,5-Difluoroisonicotinaldehyde(CAS: 870234-98-3)

3,5-Difluoroisonicotinaldehyde is a white crystalline solid with a molecular weight of 172.06 g/mol. It is slightly soluble in water and soluble in ethanol. This compound is known for its low reactivity under normal conditions, but it can undergo electrophilic aromatic substitution reactions under appropriate conditions.

3,5-Difluoroisonicotinaldehyde can be synthesized through the oxidation of 3,5-difluoronicotinamide using nitric acid and hydrogen peroxide. This method provides good selectivity and yield, typically around 75-85%.

3,5-Difluoroisonicotinaldehyde finds applications in the pharmaceutical industry for the synthesis of certain drugs. It is also used in analytical chemistry, particularly in sensor technology for detecting specific compounds.

When handling 3,5-Difluoroisonicotinaldehyde, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. In case of spill, use appropriate spill cleanup materials and follow safety data sheet (SDS) guidelines for disposal.