Compound Q&A

How is Methyl 6-oxo-1,6-dihydropyridazine-4-carboxylate (CAS: 89640-81-3) typically synthesized?

Answer

Methyl 6-oxo-1,6-dihydropyridazine-4-carboxylate
Methyl 6-oxo-1,6-dihydropyridazine-4-carboxylate (CAS: 89640-81-3) can be synthesized via the condensation of methyl acetoacetate with 4-nitropyridazine, followed by reduction and hydrolysis to remove the nitro group. Typical catalysts include palladium on carbon and sodium hydroxide, with high yields and good selectivity reported in literature.

About

CAS No 89640-81-3
English Name Methyl 6-oxo-1,6-dihydropyridazine-4-carboxylate
Molecular Formula C6H6N2O3
Molecular Weight 154.13 g/mol
SMILES COC(=O)C1=CC(=O)NN=C1
InChIKey HRSILYLPPKQMEF-UHFFFAOYSA-N
Last Updated: 2025-12-29 01:16

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