7-Chloro-1H-indole-3-carbaldehyde(CAS: 1008-07-7)

7-Chloro-1H-indole-3-carbaldehyde (CAS: 1008-07-7) is a crystalline solid with a molecular weight of approximately 172.01 g/mol. It has a pungent odor. The compound is slightly soluble in water but soluble in common organic solvents like ethanol and acetonitrile. It exhibits mild reactivity with reducing agents, making it useful in synthesis reactions. The compound is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

7-Chloro-1H-indole-3-carbaldehyde (CAS: 1008-07-7) can be synthesized by the reduction of 7-chloro-1H-indole-3-carboxylic acid with sodium borohydride or lithium aluminum hydride. The reaction is carried out in a suitable organic solvent such as methanol or ethanol. The yield is typically around 70-80%, with good selectivity for the reduction of the carboxylic acid to the aldehyde. Proper use of a catalyst and appropriate conditions are essential for optimal results.

7-Chloro-1H-indole-3-carbaldehyde (CAS: 1008-07-7) is primarily used in the pharmaceutical industry for the synthesis of various indole derivatives with potential medicinal properties. It is also used in the production of certain dyes and pigments, as well as in some sensor applications due to its reactivity and specific functional groups. Its use in semiconductors and polymers is less common but not unheard of, depending on the specific chemical environment and reactivity of the compound.

When handling 7-Chloro-1H-indole-3-carbaldehyde (CAS: 1008-07-7), appropriate personal protective equipment (PPE) should be worn, including gloves, lab coat, and safety goggles. The compound should be handled in a fume hood to minimize exposure to air and to control the environment. Spills should be immediately cleaned up using appropriate absorbent materials and proper disposal methods. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures. The compound is stable under normal conditions but avoid contact with water and strong oxidizers to prevent unexpected reactions.